Tg(MMTV-Cdc37)2Stp
Transgene Detail

Summary

• Symbol: Tg(MMTV-Cdc37)2Stp
• Name: transgene insertion 2, Lilia Stepanova
• MGI ID: MGI:3802909
• Synonyms: MMTV-CDC37.2
• Transgene: Tg(MMTV-Cdc37)2Stp Location: unknown
• Alliance: Tg(MMTV-Cdc37)2Stp page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(MMTV-Cdc37)2Stp expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cdc37 (MGI:109531)

• Mutation details: An MMTV-CDC37 transgene was generated by cloning a XhoI fragment containing the 1.6-kb mouse CDC37 open reading frame (ORF) into a plasmid containing an MMTV promoter, beta-globin splice sequences, and bGH polyadenylation sequences. (J:62465)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:62465 Stepanova L, et al., The oncoprotein kinase chaperone CDC37 functions as an oncogene in mice and collaborates with both c-myc and cyclin D1 in transformation of multiple tissues. Mol Cell Biol. 2000 Jun;20(12):4462-73
• All: 1 reference(s)