Fbln1^{Gt(XST011)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Fbln1^{Gt(XST011)Byg}
• Name: fibulin 1; gene trap XST011, BayGenomics
• MGI ID: MGI:3802971
• Synonyms: Fbln-1^-
• Gene: Fbln1 Location: Chr15:85090150-85170495 bp, + strand Genetic Position: Chr15, 40.27 cM, cytoband E-F
• Alliance: Fbln1^{Gt(XST011)Byg} page

Mutation origin

• Mutant Cell Line: XST011
• Germline Transmission: Earliest citation of germline transmission: J:137690
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT2TMpfs
• Mutation details: The gene trap containing a CD4 and a beta-geo cassette was inserted into exon 14. The absence of transcript was confirmd by RT-PCR on whole embryo extracts. (J:137690)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XST011	CC144567 ; (MGI Seq Detail)	5' RACE	unknown
  * GRCm39; (strand of gene trap mutagenesis)

Expression

In Mice Carrying this Mutation:	45 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	29 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbln1 Mutation: 30 strains or lines available

References

• Original: J:137690 Cooley MA, et al., Fibulin-1 is required for morphogenesis of neural crest-derived structures. Dev Biol. 2008 Jul 15;319(2):336-45
• All: 7 reference(s)