Arx^tm1Gldn
Targeted Allele Detail

Summary

• Symbol: Arx^tm1Gldn
• Name: aristaless related homeobox; targeted mutation 1, Jeffrey A Golden
• MGI ID: MGI:3803178
• Synonyms: Arx^flox
• Gene: Arx Location: ChrX:92330113-92341963 bp, + strand Genetic Position: ChrX, 41.05 cM
• Alliance: Arx^tm1Gldn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138839
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon2 of the Arx gene was flanked by loxP and frt-neoR-frt-loxP sites. The NeoR was removed by mating with B6;SJL-Tg(ACTFLPe)9205Dym/J mice. (J:138839)

Disease models

Expression

In Mice Carrying this Mutation:	79 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arx Mutation: 20 strains or lines available

Notes

ES cell line = "Sv6(T4)"

References

• Original: J:138839 Fulp CT, et al., Identification of Arx transcriptional targets in the developing basal forebrain. Hum Mol Genet. 2008;17(23):3740-60
• All: 21 reference(s)