Racgap1^tm1Mahi
Targeted Allele Detail

Summary

• Symbol: Racgap1^tm1Mahi
• Name: Rac GTPase-activating protein 1; targeted mutation 1, Masaki Hikida
• MGI ID: MGI:3803293
• Synonyms: MgcRacGAP^fl, MRG^F
• Gene: Racgap1 Location: Chr15:99518377-99549504 bp, - strand Genetic Position: Chr15, 56.13 cM
• Alliance: Racgap1^tm1Mahi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137760
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 2. (J:137760)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Racgap1 Mutation: 38 strains or lines available

References

• Original: J:137760 Yamada T, et al., Essential roles of mgcRacGAP in multilineage differentiation and survival of murine hematopoietic cells. Biochem Biophys Res Commun. 2008 Aug 8;372(4):941-6
• All: 2 reference(s)