Sfrp2^tm1Nat
Targeted Allele Detail

Summary

• Symbol: Sfrp2^tm1Nat
• Name: secreted frizzled-related protein 2; targeted mutation 1, Jeremy Nathans
• MGI ID: MGI:3803335
• Synonyms: sFRP2 KO
• Gene: Sfrp2 Location: Chr3:83673628-83681621 bp, + strand Genetic Position: Chr3, 37.37 cM
• Alliance: Sfrp2^tm1Nat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137889
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first coding exon of the gene, coding for the cysteine rich domain, was replaced with the bacterial beta-Gal reporter gene and the PGKneo selectable marker, both in the plus orientation. (J:137889)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sfrp2 Mutation: 30 strains or lines available

References

• Original: J:137889 Nathans J, Generation of an Sfrp2 mutant allele. MGI Direct Data Submission. 2008
• All: 1 reference(s)