Rpsa^tm1Ells
Targeted Allele Detail

Summary

• Symbol: Rpsa^tm1Ells
• Name: ribosomal protein SA; targeted mutation 1, Steven Ellis
• MGI ID: MGI:3803603
• Synonyms: LAMR1^-
• Gene: Rpsa Location: Chr9:119956832-119961435 bp, + strand Genetic Position: Chr9, 71.41 cM
• Alliance: Rpsa^tm1Ells page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138267
• Parent Cell Line: iTL1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A targeting vector containing the neomycin resistance gene was used to disrupt exons 1-4. The construct was electroporated into 129S6/SvEvTac derived iTL1 embryonic stem (ES) cells. (J:138267)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rpsa Mutation: 27 strains or lines available

References

• Original: J:138267 Han J, et al., LAMR1 (+/-) mice as a model for Diamond-Blackfan Anemia. MGI Direct Data Submission. 2008
• All: 2 reference(s)