Del(16Tssk1-Tssk2)1Joch
Targeted Allele Detail

Summary

• Symbol: Del(16Tssk1-Tssk2)1Joch
• Name: deletion, Chr 1, John C Herr 1
• MGI ID: MGI:3803634
• Synonyms: Del1Joch, Tssk1/Tssk2^tm1Joch
• Gene: Del(16Tssk1-Tssk2)1Joch Location: unknown Genetic Position: Chr16, Syntenic

Mutation origin

• Mouse Generated: Earliest citation of chimera generation: J:137707
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(16Tssk1-Tssk2)1Joch involves 2 genes/genome features (Tssk1, Tssk2) View all
• Both open reading frames for Tssk1 and Tssk2 were replaced with an frt-flanked neo cassette. (J:137707)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(16Tssk1-Tssk2)1Joch Mutation: 0 strains or lines available

References

• Original: J:137707 Xu B, et al., Targeted deletion of Tssk1 and 2 causes male infertility due to haploinsufficiency. Dev Biol. 2008 Jul 15;319(2):211-22
• All: 1 reference(s)