Tg(Aicda-cre)9Mbu
Transgene Detail

Summary

• Symbol: Tg(Aicda-cre)9Mbu
• Name: transgene insertion 9, Meinrad Busslinger
• MGI ID: MGI:3803651
• Synonyms: Aicda-cre, AID-cre
• Transgene: Tg(Aicda-cre)9Mbu Location: unknown
• Alliance: Tg(Aicda-cre)9Mbu page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Aicda-cre)9Mbu expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Aicda (MGI:1342279)

• Mutation details: BAC RP24-68I7 was used to create a transgene in which the expression of cre was under the control of the Aicda promoter by inserting cre linked by an IRES to a truncated human CD2 sequence downstream of exon 2. Line 9 was used for further research. (J:137719)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Aicda (mouse) Summary of all recombinase alleles driven by Aicda. Comparative matrix view of recombinase activities Alliance mouse Aicda gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:137719 Kwon K, et al., Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development. Immunity. 2008 Jun;28(6):751-62
• All: 29 reference(s)