Gt(ROSA)26Sor^tm1(HA)Libl
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1(HA)Libl
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Roland S Liblau
• MGI ID: MGI:3803958
• Synonyms: Rosa26^rtm(HA)1Lib
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1(HA)Libl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137838
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• Mutation details: A floxed neo cassette with a STOP preceeded by a hemagglutinin (HA) cDNA was inserted into the locus. Cre extraction of the neo-STOP cassette is necessary to acheive expression of the HA cDNA. (J:137838)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:137838 Saxena A, et al., Cutting edge: Multiple sclerosis-like lesions induced by effector CD8 T cells recognizing a sequestered antigen on oligodendrocytes. J Immunol. 2008 Aug 1;181(3):1617-21
• All: 6 reference(s)