Ifitm3^tm1Masu
Targeted Allele Detail

Summary

• Symbol: Ifitm3^tm1Masu
• Name: interferon induced transmembrane protein 3; targeted mutation 1, M Azim Surani
• MGI ID: MGI:3803977
• Synonyms: Ifitm3^EGFP, Ifitm3egfp
• Gene: Ifitm3 Location: Chr7:140589503-140590657 bp, - strand Genetic Position: Chr7, 86.25 cM, cytoband F5
• Alliance: Ifitm3^tm1Masu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137940
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: EGFP was inserted into exon 1 and a floxed puromycin resistance cassette was inserted downstream of the coding sequence. Transient cre expression in ES cells was used to remove the puro cassette. (J:137940)

Expression

In Mice Carrying this Mutation:

11 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ifitm3 Mutation: 25 strains or lines available

References

• Original: J:137940 Lange UC, et al., Normal germ line establishment in mice carrying a deletion of the Ifitm/Fragilis gene family cluster. Mol Cell Biol. 2008 Aug;28(15):4688-96
• All: 17 reference(s)