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Ifitm3tm1Masu
Targeted Allele Detail
Summary
Symbol: Ifitm3tm1Masu
Name: interferon induced transmembrane protein 3; targeted mutation 1, M Azim Surani
MGI ID: MGI:3803977
Synonyms: Ifitm3egfp, Ifitm3EGFP
Gene: Ifitm3  Location: Chr7:140589503-140590657 bp, - strand  Genetic Position: Chr7, 86.25 cM, cytoband F5
Alliance: Ifitm3tm1Masu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137940
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsEGFP was inserted into exon 1 and a floxed puromycin resistance cassette was inserted downstream of the coding sequence. Transient cre expression in ES cells was used to remove the puro cassette. (J:137940)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 11 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ifitm3 Mutation:  23 strains or lines available
References
Original:  J:137940 Lange UC, et al., Normal germ line establishment in mice carrying a deletion of the Ifitm/Fragilis gene family cluster. Mol Cell Biol. 2008 Aug;28(15):4688-96
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory