Mib2^tm1Kong
Targeted Allele Detail

Summary

• Symbol: Mib2^tm1Kong
• Name: mindbomb E3 ubiquitin protein ligase 2; targeted mutation 1, Young-Yun Kong
• MGI ID: MGI:3804450
• Gene: Mib2 Location: Chr4:155739134-155753655 bp, - strand Genetic Position: Chr4, 86.86 cM
• Alliance: Mib2^tm1Kong page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130369
• Parent Cell Line: E14K (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Intragenic deletion
• Mutation details: Exons 5 through 15 were replaced with an IRES-lacZ and puromycin resistance cassette. The absence of transcript expression was confirmed by RT-PCR analysis. (J:130369)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mib2 Mutation: 61 strains or lines available

References

• Original: J:130369 Koo BK, et al., An obligatory role of mind bomb-1 in notch signaling of Mammalian development. PLoS One. 2007;2(11):e1221
• All: 2 reference(s)