Fgf16^tm1Paca
Targeted Allele Detail

Summary

• Symbol: Fgf16^tm1Paca
• Name: fibroblast growth factor 16; targeted mutation 1, Peter A Cattini
• MGI ID: MGI:3804709
• Gene: Fgf16 Location: ChrX:104807885-104818545 bp, + strand Genetic Position: ChrX, 47.2 cM, cytoband C3
• Alliance: Fgf16^tm1Paca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138004
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a lacZ/neo cassette. The absence of transcipt expression was confirmed by RT-PCR analysis on E9.5 head extracts. (J:138004)

Expression

In Mice Carrying this Mutation:	11 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf16 Mutation: 7 strains or lines available

References

• Original: J:138004 Lu SY, et al., FGF-16 is required for embryonic heart development. Biochem Biophys Res Commun. 2008 Aug 22;373(2):270-4
• All: 1 reference(s)