Nr2e3^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Nr2e3^tm1Dgen
• Name: nuclear receptor subfamily 2, group E, member 3; targeted mutation 1, Deltagen
• MGI ID: MGI:3805457
• Gene: Nr2e3 Location: Chr9:59850054-59867942 bp, - strand Genetic Position: Chr9, 32.35 cM
• Alliance: Nr2e3^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138242
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence and intronic sequences in exon 1 through exon 8 were replaced with an IRES, LacZ and neo cassette. The absence of transcript expression as confirmed by microarray hybridization. (J:138242)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr2e3 Mutation: 22 strains or lines available

References

• Original: J:138242 Webber AL, et al., Dual role of Nr2e3 in photoreceptor development and maintenance. Exp Eye Res. 2008 Jul;87(1):35-48
• All: 1 reference(s)