Bhlhe41^tm1Mjro
Targeted Allele Detail

Summary

• Symbol: Bhlhe41^tm1Mjro
• Name: basic helix-loop-helix family, member e41; targeted mutation 1, Moritz J Rossner
• MGI ID: MGI:3805461
• Synonyms: S1^-, Sharp-1^-
• Gene: Bhlhe41 Location: Chr6:145803969-145811146 bp, - strand Genetic Position: Chr6, 77.7 cM, cytoband G2-G3
• Alliance: Bhlhe41^tm1Mjro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138240
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 3, which encodes the DNA binding domain, was replaced with a neo cassette. (J:138240)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bhlhe41 Mutation: 12 strains or lines available

References

• Original: J:138240 Rossner MJ, et al., Disturbed clockwork resetting in Sharp-1 and Sharp-2 single and double mutant mice. PLoS One. 2008;3(7):e2762
• All: 11 reference(s)