Foxq1^tm1Wen
Targeted Allele Detail

Summary

• Symbol: Foxq1^tm1Wen
• Name: forkhead box Q1; targeted mutation 1, Wolfgang Engel
• MGI ID: MGI:3805482
• Gene: Foxq1 Location: Chr13:31742153-31744959 bp, + strand Genetic Position: Chr13, 13.46 cM
• Alliance: Foxq1^tm1Wen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138249
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame was replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on stomach extracts. (J:138249)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxq1 Mutation: 29 strains or lines available

References

• Original: J:138249 Goering W, et al., Impairment of gastric acid secretion and increase of embryonic lethality in Foxq1-deficient mice. Cytogenet Genome Res. 2008;121(2):88-95
• All: 1 reference(s)