Eppk1tm1Gwi
Targeted Allele Detail
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| Symbol: |
Eppk1tm1Gwi |
| Name: |
epiplakin 1; targeted mutation 1, Gerhard Wiche |
| MGI ID: |
MGI:3805682 |
| Synonyms: |
epiplakin- |
| Gene: |
Eppk1 Location: Chr15:75973337-76004395 bp, - strand Genetic Position: Chr15, 35.37 cM
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| Alliance: |
Eppk1tm1Gwi page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:138604
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| Parent Cell Line: |
E14.1 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The first 2,697 bp of the second exon of the gene locus was replaced by an in-frame GFP gene, a floxed neomycin resistance cassette and a thymidine kinase gene. Gene inactivation was confirmed by a lack of protein expression in liver and skin.
(J:138604)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Eppk1 Mutation: |
39 strains or lines available
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| Original: |
J:138604 Spazierer D, et al., Epiplakin is dispensable for skin barrier function and for integrity of keratin network cytoarchitecture in simple and stratified epithelia. Mol Cell Biol. 2006 Jan;26(2):559-68 |
| All: |
4 reference(s) |
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Analysis Tools
