Prdm14^tm1Sait
Targeted Allele Detail

Summary

• Symbol: Prdm14^tm1Sait
• Name: PR domain containing 14; targeted mutation 1, Mitinori Saitou
• MGI ID: MGI:3805889
• Gene: Prdm14 Location: Chr1:13183681-13197387 bp, - strand Genetic Position: Chr1, 4.1 cM
• Alliance: Prdm14^tm1Sait page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138571
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region of exon 2 through 5 was replaced with a floxed neo cassette. Germ line, cre-mediated recombination was used to remove the neo cassette. (J:138571)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdm14 Mutation: 51 strains or lines available

References

• Original: J:138571 Yamaji M, et al., Critical function of Prdm14 for the establishment of the germ cell lineage in mice. Nat Genet. 2008 Aug;40(8):1016-22
• All: 3 reference(s)