Tg(Kap-icre)29066/2Sig
Transgene Detail

Summary

• Symbol: Tg(Kap-icre)29066/2Sig
• Name: transgene insertion 29066/2, Curt Sigmund
• MGI ID: MGI:3806307
• Synonyms: KAP2-iCre, Tg(Kap-cre)29066/2Sig
• Transgene: Tg(Kap-icre)29066/2Sig Location: unknown
• Alliance: Tg(Kap-icre)29066/2Sig page

Transgene origin

• Strain of Origin: C57BL/6J x SJL

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: androgen
• Mutation: Insertion
• Tg(Kap-icre)29066/2Sig expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Kap

• Mutation details: The Kap promoter is used to drive androgen inducible improved cre (crei) in the kidney. Twenty-six founders were created of which only line 29066/2 expressed cre in male kidneys with some expression in the brain, liver, and heart. (J:137742)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Kap (species not specified) Summary of all recombinase alleles driven by Kap. Comparative matrix view of recombinase activities

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:137742 Li H, et al., An androgen-inducible proximal tubule-specific Cre recombinase transgenic model. Am J Physiol Renal Physiol. 2008 Jun;294(6):F1481-6
• All: 15 reference(s)