Rtn4r^tm1.1Pado
Targeted Allele Detail

Summary

• Symbol: Rtn4r^tm1.1Pado
• Name: reticulon 4 receptor; targeted mutation 1.1, Patrick Doherty
• MGI ID: MGI:3806671
• Synonyms: NgR1^d
• Gene: Rtn4r Location: Chr16:17945506-17970272 bp, + strand Genetic Position: Chr16, 11.23 cM, cytoband B1
• Alliance: Rtn4r^tm1.1Pado page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138580
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exon 2. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:138580)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rtn4r Mutation: 24 strains or lines available

References

• Original: J:138580 Williams G, et al., Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists. J Biol Chem. 2008 Jun 13;283(24):16641-52
• All: 4 reference(s)