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Rtn4rl2tm1.1Pado
Targeted Allele Detail
Summary
Symbol: Rtn4rl2tm1.1Pado
Name: reticulon 4 receptor-like 2; targeted mutation 1.1, Patrick Doherty
MGI ID: MGI:3806672
Synonyms: NgR2d
Gene: Rtn4rl2  Location: Chr2:84702268-84717054 bp, - strand  Genetic Position: Chr2, 49.45 cM
Alliance: Rtn4rl2tm1.1Pado page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138580
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination was used to remove exon 2. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:138580)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rtn4rl2 Mutation:  24 strains or lines available
References
Original:  J:138580 Williams G, et al., Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists. J Biol Chem. 2008 Jun 13;283(24):16641-52
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory