About   Help   FAQ
Rtn4rl2tm1.1Pado
Targeted Allele Detail
Summary
Symbol: Rtn4rl2tm1.1Pado
Name: reticulon 4 receptor-like 2; targeted mutation 1.1, Patrick Doherty
MGI ID: MGI:3806672
Synonyms: NgR2d
Gene: Rtn4rl2  Location: Chr2:84702268-84717054 bp, - strand  Genetic Position: Chr2, 49.45 cM
Alliance: Rtn4rl2tm1.1Pado page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138580
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination was used to remove exon 2. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:138580)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rtn4rl2 Mutation:  24 strains or lines available
References
Original:  J:138580 Williams G, et al., Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists. J Biol Chem. 2008 Jun 13;283(24):16641-52
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory