Apom^tm1Stf
Targeted Allele Detail

Summary

• Symbol: Apom^tm1Stf
• Name: apolipoprotein M; targeted mutation 1, Markus Stoffel
• MGI ID: MGI:3806679
• Gene: Apom Location: Chr17:35347973-35350777 bp, - strand Genetic Position: Chr17, 18.59 cM, cytoband B2
• Alliance: Apom^tm1Stf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138581
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: All the coding exons were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on plasma extracts. (J:138581)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Apom Mutation: 9 strains or lines available

References

• Original: J:138581 Wolfrum C, et al., Foxa2 activity increases plasma high density lipoprotein levels by regulating apolipoprotein M. J Biol Chem. 2008 Jun 13;283(24):16940-9
• All: 1 reference(s)