Tg(CD2-rtTA)CRza
Transgene Detail

Summary

• Symbol: Tg(CD2-rtTA)CRza
• Name: transgene insertion C, Rose Zamoyska
• MGI ID: MGI:3806709
• Synonyms: rtTA,C, rtTA^huCD2
• Transgene: Tg(CD2-rtTA)CRza Location: unknown
• Alliance: Tg(CD2-rtTA)CRza page

Transgene origin

• Strain of Origin: (CBA x C57BL/10)F2

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: A fragment coding for rtTA was inserted in the human CD2 promoter. Four transgenic lines were produced. Line A contains one copy. Line D contains 5 copies. Line C, which was chosen as the representative line, contains 3 copies. (J:110527, J:174339)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:110527 Legname G, et al., Inducible expression of a p56Lck transgene reveals a central role for Lck in the differentiation of CD4 SP thymocytes. Immunity. 2000 May;12(5):537-46
• All: 16 reference(s)