Tg(H2-K-MC159/EGFP)13Fkmc
Transgene Detail

Summary

• Symbol: Tg(H2-K-MC159/EGFP)13Fkmc
• Name: transgene insertion 13, Francis Ka-Ming Chan
• MGI ID: MGI:3806951
• Synonyms: MC159-GFP
• Transgene: Tg(H2-K-MC159/EGFP)13Fkmc Location: unknown
• Alliance: Tg(H2-K-MC159/EGFP)13Fkmc page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The H2-B^b promoter was used to drive expression of a programmed cell death inhibitor MC159 from the virus Molluscum contagiosum. Eleven founders were created with line 13 exhibiting the strongest expression in multiple tissues. (J:138050)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:138050 Woelfel M, et al., Transgenic expression of the viral FLIP MC159 causes lpr/gld-like lymphoproliferation and autoimmunity. J Immunol. 2006 Sep 15;177(6):3814-20
• All: 1 reference(s)