Tg(Cyp17a1-icre)AJako
Transgene Detail

Summary

• Symbol: Tg(Cyp17a1-icre)AJako
• Name: transgene insertion A, CheMyong Ko
• MGI ID: MGI:3807212
• Synonyms: Cyp17iCre, TC^Cre, Tg(Cyp17a1-cre)ACmk
• Transgene: Tg(Cyp17a1-icre)AJako Location: unknown
• Alliance: Tg(Cyp17a1-icre)AJako page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Cyp17a1-icre)AJako expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Cyp17a1

• Mutation details: The promoter was used to drive expression of a codon improved cre in the theca/interstitial cells of the ovary and Leydig cells of the testes. Three lines (lines A, B and C) were created. While all lines exhibit gonadal expression, line B and C exhibit extra-gonadal expression. (J:138920)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cyp17a1 (species not specified) Summary of all recombinase alleles driven by Cyp17a1. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:138920 Bridges PJ, et al., Generation of Cyp17iCre transgenic mice and their application to conditionally delete estrogen receptor alpha (Esr1) from the ovary and testis. Genesis. 2008 Sep 9;46(9):499-505
• All: 20 reference(s)