Hmx1^dmbo
Chemically induced Allele Detail

Summary

• Symbol: Hmx1^dmbo
• Name: H6 homeobox 1; dumbo
• MGI ID: MGI:3807705
• Synonyms: dumbo, Hmx1^dm
• Gene: Hmx1 Location: Chr5:35546452-35557074 bp, + strand Genetic Position: Chr5, 18.14 cM
• Alliance: Hmx1^dmbo page

Ear and cranial malformations in Hmx1^dmbo/Hmx1^dmbo mice

Show the 5 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

Allele Type: Chemically induced (ENU) Mutation: Single point mutation A single C to T mutation changes GLU65 to an amber stop codon (J:147782) Inheritance: Recessive

Identification of the point mutation in the dmbo allele of Hmx1

Disease models

Expression

In Mice Carrying this Mutation:	18 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hmx1 Mutation: 10 strains or lines available

References

• Original: J:100332 Wilson L, et al., Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations. Genome Res. 2005 Aug;15(8):1095-105
• All: 7 reference(s)