Sox1^tm1(cre)Take
Targeted Allele Detail

Summary

• Symbol: Sox1^tm1(cre)Take
• Name: SRY (sex determining region Y)-box 1; targeted mutation 1, Takumi Era
• MGI ID: MGI:3807952
• Synonyms: Sox1-Cre
• Gene: Sox1 Location: Chr8:12445519-12449555 bp, + strand Genetic Position: Chr8, 5.73 cM, cytoband A1-A2
• Alliance: Sox1^tm1(cre)Take page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138918
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Sox1^tm1(cre)Take expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Sox1 (MGI:98357)

• Mutation details: Cre recombines cDNA was inserted into the ATG codon start site of Sox1 by in-frame. PGK-NEO cassette was removed by transient Flp recombinase expression. (J:138918)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sox1 (mouse) Summary of all recombinase alleles driven by Sox1. Comparative matrix view of recombinase activities Alliance mouse Sox1 gene page

Disease models

Expression

In Mice Carrying this Mutation:

54 assay results 7 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sox1 Mutation: 13 strains or lines available

References

• Original: J:138918 Takashima Y, et al., Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell. 2007 Jun 29;129(7):1377-88
• All: 34 reference(s)