Tyrp1^rgsc892
Chemically induced Allele Detail

Summary

• Symbol: Tyrp1^rgsc892
• Name: tyrosinase-related protein 1; RIKEN Genomic Sciences Center (GSC), 892
• MGI ID: MGI:3807981
• Synonyms: M100892
• Gene: Tyrp1 Location: Chr4:80752360-80769956 bp, + strand Genetic Position: Chr4, 37.89 cM
• Alliance: Tyrp1^rgsc892 page

Mutation origin

• Strain of Origin: C57BL/6JJcl
• Project Collection: RIKEN GSC ENU Project

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• Mutation details: This mutation was identified among the progeny of an ENU mutagenized male mouse. Its failure to complement the classic brown mutation, Tyrp1^b, suggests the two are allelic.
• Inheritance: Recessive

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
Loading...
hm1	Tyrp1^rgsc892/Tyrp1^rgsc892	involves: C57BL/6JJcl * DBA/2JJcl

Phenotypes:

Affected Systems	hm1
show or hide all annotated terms
integument	√
abnormal coat/hair pigmentation	√
pigmentation	√
abnormal coat/hair pigmentation	√

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tyrp1 Mutation: 162 strains or lines available

References

• Original: J:133634 RIKEN BioResource Center/RIKEN Genomic Sciences Center, A Large Scale Mutagenesis Program in RIKEN GSC. PhenoSITE, World Wide Web (URL: http://www.brc.riken.jp/lab/gsc/mouse/). 2008
• All: 1 reference(s)