Tg(CAG-LacZ,-Pth2)1Tbu
Transgene Detail

Summary

• Symbol: Tg(CAG-LacZ,-Pth2)1Tbu
• Name: transgene insertion 1, Ted B Usdin
• MGI ID: MGI:3807998
• Synonyms: Tg^{FlxStpTip39cDNA}
• Transgene: Tg(CAG-LacZ,-Pth2)1Tbu Location: unknown
• Alliance: Tg(CAG-LacZ,-Pth2)1Tbu page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-LacZ,-Pth2)1Tbu expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pth2 (MGI:2152297)

• Mutation details: A transgenic construct was designed with the CMV enhancer/chicken beta-actin promoter, loxP-flanked STOP sequence (beta-geo reporter followed by SV40 polyadenylation signal), and a mouse Pth2 cDNA. When bred to mice expressing Cre recombinase expressing mice in specific tissues, the STOP sequence (and beta-geo) is removed allowing expression of Pth2 in Cre-expressing cells. (J:138142)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:138142 Usdin TB, et al., Tuberoinfundibular Peptide of 39 residues is required for germ cell development. Endocrinology. 2008 Sep;149(9):4292-300
• All: 1 reference(s)