Gpr158^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Gpr158^{tm1(KOMP)Vlcg}
• Name: G protein-coupled receptor 158; targeted mutation 1, Velocigene
• MGI ID: MGI:3808194
• Synonyms: Gpr158^tm1Vlcg
• Gene: Gpr158 Location: Chr2:21372378-21835355 bp, + strand Genetic Position: Chr2, 14.92 cM
• Alliance: Gpr158^{tm1(KOMP)Vlcg} page
• IMPC: Gpr158 gene page

Mutation origin

• Mutant Cell Lines: 10108A-A5, 10108C-F3
• Germline Transmission: Earliest citation of germline transmission: J:232911
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 31129bp between positions 21373050-21404178 of Chromosome 2 (Build GRCm39). The first two exons encoding 1/3 of the entire protein sequence were replaced with a LacZ cassette containing a stop codon. (J:136110, J:232911)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Gpr158 Mutation: 75 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 13 reference(s)