Nhlrc1^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Nhlrc1^{tm1(KOMP)Vlcg}
• Name: NHL repeat containing 1; targeted mutation 1, Velocigene
• MGI ID: MGI:3808349
• Synonyms: Epm2b^-, malin^KO
• Gene: Nhlrc1 Location: Chr13:47166033-47168326 bp, - strand Genetic Position: Chr13, 24.5 cM
• Alliance: Nhlrc1^{tm1(KOMP)Vlcg} page
• IMPC: Nhlrc1 gene page

Lafora bodies in tissues of Nhlrc1^{tm1(KOMP)Vlcg}/Nhlrc1^{tm1(KOMP)Vlcg} mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Lines: 10571D-E2, 10571E-H8
• Germline Transmission: Earliest citation of germline transmission: J:165994
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1 Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1574bp between positions 47166679-47168252 of Chromosome 13 (Build GRCm39). (J:136110)

Generation of the Nhlrc1^tm1(KOMP)Vlcg allele

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Nhlrc1 Mutation: 16 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 11 reference(s)