Ifi27l2a^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Ifi27l2a^{tm1(KOMP)Vlcg}
• Name: interferon, alpha-inducible protein 27 like 2A; targeted mutation 1, Velocigene
• MGI ID: MGI:3808494
• Synonyms: Ifi27l2a^tm1Vlcg
• Gene: Ifi27l2a Location: Chr12:103408426-103409939 bp, - strand Genetic Position: Chr12, 52.93 cM, cytoband F1
• Alliance: Ifi27l2a^{tm1(KOMP)Vlcg} page
• IMPC: Ifi27l2a gene page

Mutation origin

• Mutant Cell Lines: 10949A-A10, 10949A-F1, 10949A-F10, 10949A-H8
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1324bp between positions 103408566-103409889 of Chromosome 12 (Build GRCm39). Exon 3 was deleted and replaced with a loxP flanked neomycin selection cassette and an lacZ reporter gene. (J:136110, J:221531)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Ifi27l2a Mutation: 11 strains or lines available

Notes

Mice used in J:221531 were created using ES cell clone 10949A-H8.

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 4 reference(s)