Tg(Pbsn-SFRP1)1Pcma
Transgene Detail

Summary

• Symbol: Tg(Pbsn-SFRP1)1Pcma
• Name: transgene insertion 1, Paul C Marker
• MGI ID: MGI:3808599
• Synonyms: PB-SFRP1
• Transgene: Tg(Pbsn-SFRP1)1Pcma Location: unknown
• Alliance: Tg(Pbsn-SFRP1)1Pcma page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pbsn-SFRP1)1Pcma expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SFRP1 (6422)

  Sfrp1

  (MGI:892014)

• Mutation details: A full length human SFRP1 cDNA was placed under the control of the rat probasin promoter (Pbsn). Three founder animals were identified. Over-expression in the prostate was confirmed by immunoblotting. (J:136160)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:136160 Joesting MS, et al., Secreted frizzled related protein 1 is a paracrine modulator of epithelial branching morphogenesis, proliferation, and secretory gene expression in the prostate. Dev Biol. 2008 May 1;317(1):161-73
• All: 1 reference(s)