Ffar2^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Ffar2^tm1Lex
• Name: free fatty acid receptor 2; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3808703
• Synonyms: GPR43 KO
• Gene: Ffar2 Location: Chr7:30517778-30523200 bp, - strand Genetic Position: Chr7, 19.25 cM
• Alliance: Ffar2^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138134
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The exon containing the entire coding region was replaced with a neo selection cassette. (J:138134)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ffar2 Mutation: 25 strains or lines available

References

• Original: J:138134 Ge H, et al., Activation of g protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free Fatty acids. Endocrinology. 2008 Sep;149(9):4519-26
• All: 8 reference(s)