Kcnk7^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Kcnk7^tm1Dgen
• Name: potassium channel, subfamily K, member 7; targeted mutation 1, Deltagen
• MGI ID: MGI:3808709
• Gene: Kcnk7 Location: Chr19:5754395-5757137 bp, + strand Genetic Position: Chr19, 4.34 cM, cytoband B2
• Alliance: Kcnk7^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:139187
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neomycin cassette. Gene inactivation was confirmed by a lack of mRNA or protein derived from the gene locus. (J:139187)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnk7 Mutation: 19 strains or lines available

References

• Original: J:139187 Yost CS, et al., Knockout of the gene encoding the K(2P) channel KCNK7 does not alter volatile anesthetic sensitivity. Behav Brain Res. 2008 Nov 21;193(2):192-6
• All: 1 reference(s)