Crisp1^tm1Pasc
Targeted Allele Detail

Summary

• Symbol: Crisp1^tm1Pasc
• Name: cysteine-rich secretory protein 1; targeted mutation 1, Patricia Cuasnicu
• MGI ID: MGI:3808726
• Gene: Crisp1 Location: Chr17:40604649-40630098 bp, - strand Genetic Position: Chr17, 19.47 cM
• Alliance: Crisp1^tm1Pasc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:139154
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on epididymal extracts. (J:139154)

Expression

In Mice Carrying this Mutation:

26 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crisp1 Mutation: 19 strains or lines available

References

• Original: J:139154 Da Ros VG, et al., Impaired sperm fertilizing ability in mice lacking Cysteine-RIch Secretory Protein 1 (CRISP1). Dev Biol. 2008 Aug 1;320(1):12-8
• All: 5 reference(s)