Slc16a8^tm1Njp
Targeted Allele Detail

Summary

• Symbol: Slc16a8^tm1Njp
• Name: solute carrier family 16 (monocarboxylic acid transporters), member 8; targeted mutation 1, Nancy J Philp
• MGI ID: MGI:3809596
• Synonyms: Mct3^-
• Gene: Slc16a8 Location: Chr15:79135214-79138961 bp, - strand Genetic Position: Chr15, 37.7 cM, cytoband E2
• Alliance: Slc16a8^tm1Njp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138634
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 2-4 which encode the first 11 predicted transmembrane domains were deleted. No protein was detectable by western blot in the retinal pigment epithelium. (J:138634)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc16a8 Mutation: 13 strains or lines available

References

• Original: J:138634 Daniele LL, et al., Altered visual function in monocarboxylate transporter 3 (Slc16a8) knockout mice. Am J Physiol Cell Physiol. 2008 Aug;295(2):C451-7
• All: 1 reference(s)