Sgo2a^{Gt(D025B05)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Sgo2a^{Gt(D025B05)Wrst}
• Name: shugoshin 2A; gene trap D025B05, Wolfgang Wurst
• MGI ID: MGI:3809644
• Gene: Sgo2a Location: Chr1:58035130-58065058 bp, + strand Genetic Position: Chr1, 28.86 cM
• Alliance: Sgo2a^{Gt(D025B05)Wrst} page

Mutation origin

• Mutant Cell Line: D025B05
• Germline Transmission: Earliest citation of germline transmission: J:138779
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: rFlpROSAbetageo
• Mutation details: An rFlpROSA-Betageo vector was inserted into the first intron. Absence of transcript and protein was confirmed by Northern blot, RT-PCR and immunofluorescence analysis. (J:138779)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  D025B05	DU822180 ; (MGI Seq Detail)	5' RACE	Chr1:58035320-58035470 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  33 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sgo2a Mutation: 53 strains or lines available

References

• Original: J:138779 Llano E, et al., Shugoshin-2 is essential for the completion of meiosis but not for mitotic cell division in mice. Genes Dev. 2008 Sep 1;22(17):2400-13
• All: 9 reference(s)