Rad9a^tm2Lieb
Targeted Allele Detail

Summary

• Symbol: Rad9a^tm2Lieb
• Name: RAD9 checkpoint clamp component A; targeted mutation 2, Howard B Lieberman
• MGI ID: MGI:3809875
• Synonyms: Mrad9^Tar
• Gene: Rad9a Location: Chr19:4245195-4251661 bp, - strand Genetic Position: Chr19, 3.89 cM, cytoband A
• Alliance: Rad9a^tm2Lieb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92282
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted 5' to exon 1 and a FRT flanked neomycin selection cassette was inserted in intron 2. A second loxP site was placed 3' to the selection cassette. Mice carrying this mutant allele were used in the creation of Rad9^tm1Lieb (J:92282)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rad9a Mutation: 27 strains or lines available

References

• Original: J:92282 Hopkins KM, et al., Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality. Mol Cell Biol. 2004 Aug;24(16):7235-48
• All: 6 reference(s)