Sfrp2^tm1Ktas
Targeted Allele Detail

Summary

• Symbol: Sfrp2^tm1Ktas
• Name: secreted frizzled-related protein 2; targeted mutation 1, Kei Tashiro
• MGI ID: MGI:3810257
• Gene: Sfrp2 Location: Chr3:83673628-83681621 bp, + strand Genetic Position: Chr3, 37.37 cM
• Alliance: Sfrp2^tm1Ktas page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138805
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neo cassette via homologous recombination. RT-PCR and in situ hybridization analysis confirmed the absence of transcript and protein in homozygotes. (J:138805)

Expression

In Mice Carrying this Mutation:	22 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sfrp2 Mutation: 30 strains or lines available

References

• Original: J:138805 Ikegawa M, et al., Syndactyly and preaxial synpolydactyly in the single Sfrp2 deleted mutant mice. Dev Dyn. 2008 Sep;237(9):2506-17
• All: 1 reference(s)