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Cacng3tm1Ran
Targeted Allele Detail
Summary
Symbol: Cacng3tm1Ran
Name: calcium channel, voltage-dependent, gamma subunit 3; targeted mutation 1, Roger A Nicoll
MGI ID: MGI:3810416
Synonyms: gamma-3-, TARP gamma-3-
Gene: Cacng3  Location: Chr7:122270967-122368616 bp, + strand  Genetic Position: Chr7, 66.81 cM, cytoband F3
Alliance: Cacng3tm1Ran page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138791
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo-cassette replaced exon 2 and part of 3 via homologous recombination. Immunoblot analysis of brain lysates from homozygous mice confirmed the absence of protein. (J:138791)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cacng3 Mutation:  16 strains or lines available
References
Original:  J:138791 Menuz K, et al., TARP redundancy is critical for maintaining AMPA receptor function. J Neurosci. 2008 Aug 27;28(35):8740-6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory