Bmp4^tm2.1Blh
Targeted Allele Detail

Summary

• Symbol: Bmp4^tm2.1Blh
• Name: bone morphogenetic protein 4; targeted mutation 1, Brigid L Hogan
• MGI ID: MGI:3811252
• Synonyms: Bmp4^lacZ
• Gene: Bmp4 Location: Chr14:46620982-46628126 bp, - strand Genetic Position: Chr14, 23.95 cM
• Alliance: Bmp4^tm2.1Blh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:140013
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Germ line, cre mediated recombination was used to remove the neo cassette. The lacZ cassette is unaffected. (J:140013)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmp4 Mutation: 23 strains or lines available

References

• Original: J:140013 Corriere MA, et al., Endothelial Bmp4 is induced during arterial remodeling: effects on smooth muscle cell migration and proliferation. J Surg Res. 2008 Mar;145(1):142-9
• All: 6 reference(s)