Tg(Ggt1-cre)M3Egn
Transgene Detail

Summary

• Symbol: Tg(Ggt1-cre)M3Egn
• Name: transgene insertion M3, Eric G Neilson
• MGI ID: MGI:3811269
• Synonyms: gammaGT-Cre, gammaGT.Cre, Tg(Ggt1-cre)1Egn
• Transgene: Tg(Ggt1-cre)M3Egn Location: unknown
• Alliance: Tg(Ggt1-cre)M3Egn page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Ggt1-cre)M3Egn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Ggt1 (116568)

  Ggt1	(MGI:95706)

• Mutation details: The rat proximal promoter to Ggt1 was used in a transgene construct to drive the expression of cre recombinase, followed by a termination sequence from human growth hormone. Cre expression was limited to cortical tubular epithelium of the kidney, and was first detected around 7 days of age. (J:111660)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ggt1 (rat) Summary of all recombinase alleles driven by Ggt1. Comparative matrix view of recombinase activities Alliance rat Ggt1 gene page

Disease models

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Ggt1-cre)M3Egn

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:111660 Iwano M, et al., Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest. 2002 Aug;110(3):341-50
• All: 51 reference(s)