Tbx4^tm1.2Pa
Targeted Allele Detail

Summary

• Symbol: Tbx4^tm1.2Pa
• Name: T-box 4; targeted mutation 1.2, Virginia Papaioannou
• MGI ID: MGI:3811603
• Synonyms: Tbx4^cond
• Gene: Tbx4 Location: Chr11:85777248-85806923 bp, + strand Genetic Position: Chr11, 51.42 cM
• Alliance: Tbx4^tm1.2Pa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117423
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Germ line, cre mediated recombination was used to remove the neo cassette leaving exon 5 floxed. (J:117423)

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tbx4 Mutation: 23 strains or lines available

References

• Original: J:117423 Naiche LA, et al., Tbx4 is not required for hindlimb identity or post-bud hindlimb outgrowth. Development. 2007 Jan;134(1):93-103
• All: 6 reference(s)