Npy^tm1(cre)Tkar
Targeted Allele Detail

Summary

• Symbol: Npy^tm1(cre)Tkar
• Name: neuropeptide Y; targeted mutation 1, Tim Karl
• MGI ID: MGI:3811718
• Synonyms: NPY^-, NPY-cre
• Gene: Npy Location: Chr6:49799690-49806487 bp, + strand Genetic Position: Chr6, 24.04 cM, cytoband B3
• Alliance: Npy^tm1(cre)Tkar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:139989
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Recombinase)
• Mutation: Insertion
• Npy^tm1(cre)Tkar expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Npy (MGI:97374)

• Mutation details: Cre-recombinase was inserted into the Npy gene locus. This is a null allele. A detailed description of this targeted mutation is to appear in a future publication. (J:139989)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Npy (mouse) Summary of all recombinase alleles driven by Npy. Alliance mouse Npy gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npy Mutation: 19 strains or lines available

References

• Original: J:139989 Karl T, et al., Behavioural profile of a new mouse model for NPY deficiency. Eur J Neurosci. 2008 Jul;28(1):173-80
• All: 15 reference(s)