Tex12^tm1Hoog
Targeted Allele Detail

Summary

• Symbol: Tex12^tm1Hoog
• Name: testis expressed 12; targeted mutation 1, Christer Hoog
• MGI ID: MGI:3811722
• Gene: Tex12 Location: Chr9:50468448-50472568 bp, - strand Genetic Position: Chr9, 27.75 cM
• Alliance: Tex12^tm1Hoog page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:139993
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 5 were replaced with a floxed neo cassette. The absence of protein was confirmed by western blot analysis. (J:139993)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tex12 Mutation: 6 strains or lines available

References

• Original: J:139993 Hamer G, et al., Progression of meiotic recombination requires structural maturation of the central element of the synaptonemal complex. J Cell Sci. 2008 Aug 1;121(Pt 15):2445-51
• All: 4 reference(s)