Gck^Rgsc960
Chemically induced Allele Detail

Summary

• Symbol: Gck^Rgsc960
• Name: glucokinase; RIKEN Genomic Sciences Center (GSC), 960
• MGI ID: MGI:3811737
• Synonyms: Gck^S127P, M100960
• Gene: Gck Location: Chr11:5850820-5900081 bp, - strand Genetic Position: Chr11, 3.88 cM
• Alliance: Gck^Rgsc960 page

Mutation origin

• Strain of Origin: C57BL/6JJcl
• Project Collection: RIKEN GSC ENU Project

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation, identified in an ENU mutagenesis screen, comprises a T to C transition in exon 4 that results in replacement of serine by proline at amino acid 127 of the protein (S127P). (J:137483)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gck Mutation: 63 strains or lines available

References

• Original: J:133634 RIKEN BioResource Center/RIKEN Genomic Sciences Center, A Large Scale Mutagenesis Program in RIKEN GSC. PhenoSITE, World Wide Web (URL: http://www.brc.riken.jp/lab/gsc/mouse/). 2008
• All: 2 reference(s)