Slc4a9^tm1Ges
Targeted Allele Detail

Summary

• Symbol: Slc4a9^tm1Ges
• Name: solute carrier family 4, sodium bicarbonate cotransporter, member 9; targeted mutation 1, Gary E Shull
• MGI ID: MGI:3812007
• Synonyms: AE4^-
• Gene: Slc4a9 Location: Chr18:36661200-36689326 bp, + strand Genetic Position: Chr18, 19.46 cM
• Alliance: Slc4a9^tm1Ges page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121543
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Deficient mice were created by deleting part of exon 12 and all of exon 13, thereby eliminating codons 558-626. This mutation is predicted to terminate the open reading frame at the beginning of the transmembrane domains in the encoded protein. (J:121543)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc4a9 Mutation: 37 strains or lines available

References

• Original: J:121543 Simpson JE, et al., PAT-1 (Slc26a6) is the predominant apical membrane Cl-/HCO3- exchanger in the upper villous epithelium of the murine duodenum. Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1079-88
• All: 4 reference(s)