Sim1^Rgsc646
Chemically induced Allele Detail

Summary

• Symbol: Sim1^Rgsc646
• Name: single-minded family bHLH transcription factor 1; RIKEN Genomic Sciences Center (GSC), 646
• MGI ID: MGI:3812149
• Synonyms: M100646
• Gene: Sim1 Location: Chr10:50770850-50865248 bp, + strand Genetic Position: Chr10, 24.87 cM, cytoband B3-B4
• Alliance: Sim1^Rgsc646 page

Mutation origin

• Strain of Origin: C57BL/6JJcl
• Project Collection: RIKEN GSC ENU Project

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: This mutation, discovered in an ENU mutagenesis screen, has been identified as a GT to GA substitution in the splicing donor site of exon 9. It may result in abnormal splicing and/or nonsense mediated decay. (J:133634)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sim1 Mutation: 52 strains or lines available

References

• Original: J:133634 RIKEN BioResource Center/RIKEN Genomic Sciences Center, A Large Scale Mutagenesis Program in RIKEN GSC. PhenoSITE, World Wide Web (URL: http://www.brc.riken.jp/lab/gsc/mouse/). 2008
• All: 2 reference(s)