Ooep^{Gt(139A2)Cmhd}
Gene trapped Allele Detail

Summary

• Symbol: Ooep^{Gt(139A2)Cmhd}
• Name: oocyte expressed protein; gene trap 139A2, Centre for Modeling Human Disease
• MGI ID: MGI:3812181
• Synonyms: Floped^tm, Ooep^{Gt(139A2-3)Cmhd}
• Gene: Ooep Location: Chr9:78284185-78285870 bp, - strand Genetic Position: Chr9, 43.65 cM, cytoband E1
• Alliance: Ooep^{Gt(139A2)Cmhd} page

Mutation origin

• Mutant Cell Line: 139A2
• Germline Transmission: Earliest citation of germline transmission: J:140105
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: Gep-SD5
• Mutation details: The gene trap vector Gep-SD5, containing a beta-galactosidase and neo cassette, was inserted into intron 2. Absence of protein expression was confirmed by immunohistochemistry on ovary samples. (J:140105)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CMHD-GT_139A2-3	CL631880 ; (MGI Seq Detail)	3' RACE	Chr9:78284730-78284972 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  14 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	33 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ooep Mutation: 23 strains or lines available

Notes

This gene trap is no longer available through the Toronto Centre for Phenogenomics.

References

• Original: J:140105 Li L, et al., A subcortical maternal complex essential for preimplantation mouse embryogenesis. Dev Cell. 2008 Sep;15(3):416-25
• All: 5 reference(s)