Ccrl2^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Ccrl2^tm1Lex
• Name: C-C motif chemokine receptor-like 2; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3812407
• Gene: Ccrl2 Location: Chr9:110883902-110886586 bp, - strand Genetic Position: Chr9, 60.92 cM, cytoband F
• Alliance: Ccrl2^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:140110
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The entire coding exon was replaced with an IRES-lacZ and neo cassette. (J:140110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccrl2 Mutation: 18 strains or lines available

References

• Original: J:140110 Zabel BA, et al., Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis. J Exp Med. 2008 Sep 29;205(10):2207-20
• All: 4 reference(s)